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Current Medicinal Chemistry

Volume 28, 42 Issues, 2021
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

Aims & Scope

Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth/mini reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Articles Ahead of Print


Challenges and Perspectives in the Discovery of Dengue Virus Entry Inhibitors


Facundo N. Gallo, Ana G. Enderle, Lucas A. Pardo, Emilse S. Leal and Mariela Bollini*


DOI: 10.2174/0929867328666210521213118
View Abstract View on PubMed


The Emerging Landscapes to Drug Delivery Systems for the Treatment of Pancreatic Cancer


Agnes Magri*, Franciele Garcia Baveloni, Bruna Almeida Furquim de Camargo and Marlus Chorilli*


DOI: 10.2174/0929867328666210319144347
View Abstract View on PubMed



Recent Advances in Chalcone-Based Anticancer Heterocycles: A Structural and Molecular Target Perspective


Vishal Kumar, Sanjeev Dhawan, Pankaj Sanjay Girase, Paul Awolade, Suraj Raosaheb Shinde, Rajshekhar Karpoormath* and Parvesh Singh*


DOI: 10.2174/0929867328666210322102836
View Abstract View on PubMed





A Review of Light Sources and Enhanced Targeting for Photodynamic Therapy


Menghua Xiang, Quanming Zhou, Zihan Shi, Xuan Wang, Mengchu Li, Yan Jia, Shaoyun Li, Fen Yang, Wei Wang, Tongkai Chen, Xiaojun Xu, Bigyan Sharma, Yichu Nie, Qicai Xiao* and Liqian Gao*


DOI: 10.2174/0929867328666210121122106
View Abstract View on PubMed



Abstracts Ahead of Print

Aromatic interactions in Glycochemistry: from molecular recognition to catalysis


Andrés González Santana, Laura Díaz-Casado, Laura Montalvillo, Ester Jiménez-Moreno, Enrique Mann and Juan Luis Asensio*


DOI: 10.2174/0929867328666210709120216
View Abstract


Use of Exogenous Enzymes in Human Therapy: Approved Drugs and Potential Applications


Patrizia Cioni, Edi Gabellieri, Barbara Campanini, Stefano Bettati and Samanta Raboni*


DOI: 10.2174/0929867328666210713094722
View Abstract


Nanomaterials and Stem Cell Differentiation Potential: An Overview of Biological Aspects and Biomedical Efficacy


Ali Ehsani, Asma Jodaei, Mohammad Barzegar-Jalali, Ezzatollah Fathi, Raheleh Farahzadi* and Khosro Adibkia


DOI: 10.2174/0929867328666210712193113
View Abstract




Research Progress of DCLK1 Inhibitors as Cancer Therapeutics


Linna Cheng, Shenzhen Huang, Lijuan Chen, Xiaoyan Dong, Lei Zhang, Chengye Wu, Kaihong Ye, Fengmin Shao*, Zunmin Zhu* and Rick F. Thorne*


DOI: 10.2174/0929867328666210709110721
View Abstract


Antiprotozoal and anthelmintic activity of zinc oxide nanoparticles


José Rodrigues do Carmo Neto, Rhanoica Oliveira Guerra, Juliana Reis Machado, Anielle Christine Almeida Silva and Marcos Vinicius da Silva*


DOI: 10.2174/0929867328666210709105850
View Abstract


Epigenetics of Triple-negative breast cancer via natural compounds


Mohammed Kaleem, Maryam Perwaiz, Suza Mohammad Nur, Abdulrasheed O. Abdulrahman, Wasim Ahmad, Fahad A. Al-Abbasi, Vikas Kumar, Mohammad Amjad Kamal and Firoz Anwar*


DOI: 10.2174/0929867328666210707165530
View Abstract


The Cardiovascular Benefits of Caffeinated Beverages: Real or Surreal? / “Metron Ariston - All in Moderation”


Antonis A. Manolis*, Theodora A. Manolis , Evdoxia J. Apostolopoulos , Helen Melita and Antonis S. Manolis*


DOI: 10.2174/0929867328666210708091709
View Abstract


Synthesis and Development of Indole Based 5-HT3 Receptor Antagonists as Anti-Emetic Drugs in Oncology: An Update


Johana L. Rivera-Fonseca, Nelly González-Rivas, M. V. Basavanag Unnamatla, Marco A. García-Eleno, Horacio Reyes, L. Germán López-Valdez, David Corona-Becerril and Erick Cuevas-Yañez*


DOI: 10.2174/0929867328666210708091134
View Abstract


Published Contents

Open Access Articles

A Novel Dicationic Boron Dipyrromethene-based Photosensitizer for Antimicrobial Photodynamic Therapy against Methicillin-Resistant Staphylococcus aureus

, 2021; 28(21): 4283 - 4294

Priyanga Dharmaratne, Ligang Yu, Roy Chi-Hang Wong, Ben Chun-Lap Chan, Kit-Man Lau, Baiyan Wang, Clara Bik San Lau, Kwok-Pui Fung, Dennis Kee-Pui Ng and Margaret Ip*







Role of Alpha-Fetoprotein in Hepatocellular Carcinoma Drug Resistance

, 2021; 28(6): 1126 - 1142

Wei Li, Kun Liu, Yi Chen, Mingyue Zhu* and Mengsen Li*




Deep Learning in the Quest for Compound Nomination for Fighting COVID-19

, 2021; 28: 1 - 32 (E-Pub Ahead of Print)

Maria Mernea, Eliza. C. Martin, Andrei-José Petrescu* and Speranta Avram*




Tumor in 3D: In Vitro Complex Cellular Models to Improve Nanodrugs Cancer Therapy

, 2020; 27(42): 7234 - 7255

Soraia Fernandes*, Marco Cassani, Stefania Pagliari, Petr Filipensky, Francesca Cavalieri and Giancarlo Forte*





Osteoporosis: Current and Emerging Therapies Targeted to Immunological Checkpoints

, 2020; 27(37): 6356 - 6372

Massimo De Martinis, Maria Maddalena Sirufo and Lia Ginaldi*









Porous Inorganic and Hybrid Systems for Drug Delivery: Future Promise in Combatting Drug Resistance and Translation to Botanical Applications

, 2019; 26(33): 6107 - 6131

Junling Guo, Bruno D. Mattos, Blaise L. Tardy, Vanessa M. Moody, Gao Xiao, Hirotaka Ejima, Jiwei Cui*, Kang Liang* and Joseph J. Richardson*





Most Cited Articles


Review Article

Role of ox-LDL and LOX-1 in atherogenesis

, 2019; 26(9): 1693-1700.

Ajoe John Kattoor, Sri Harsha Kanuri and Jawahar L. Mehta*


DOI: 10.2174/0929867325666180508100950



Review Article

Targeting cxcl12/cxcr4 axis in tumor immunotherapy

, 2019; 26(17): 3026-3041.

Weiqiang Zhou, Shanchun Guo*, Mingli Liu, Matthew E. Burow and Guangdi Wang*


DOI: 10.2174/0929867324666170830111531


Review Article

Cyclooxygenase-2 inhibitors as a therapeutic target in inflammatory diseases

, 2019; 26(18): 3225-3241.

Miguel D. Ferrer, Carla Busquets-Cortés, Xavier Capó, Silvia Tejada, Josep A. Tur, Antoni Pons and Antoni Sureda*


DOI: 10.2174/0929867325666180514112124


General Review Article

Homocysteine and hyperhomocysteinaemia

, 2019; 26(16): 2948-2961.

Bozidarka L. Zaric*, Milan Obradovic, Vladan Bajic , Mohamed A. Haidara , Milos Jovanovic and Esma R. Isenovic*


DOI: 10.2174/0929867325666180313105949


Review Article

Plant-derived products as antibacterial and antifungal agents in human health care

, 2019; 26(29): 5501-5541.

Ladislav Kokoska*, Pavel Kloucek , Olga Leuner* and Pavel Novy


DOI: 10.2174/0929867325666180831144344


Review Article

ABC transporters: Regulation and association with multidrug resistance in hepatocellular carcinoma and colorectal carcinoma

, 2019; 26(7): 1224-1250.

María Paula Ceballos, Juan Pablo Rigalli, Lucila Inés Ceré, Mariana Semeniuk, Viviana Alicia Catania and María Laura Ruiz*


DOI: 10.2174/0929867325666180105103637


Review Article

Osteoporosis: Current and emerging therapies targeted to immunological checkpoints

, 2020; 27(37): 6356-6372.

Massimo De Martinis, Maria Maddalena Sirufo and Lia Ginaldi*


DOI: 10.2174/0929867326666190730113123


Review Article

Role of autophagy in Parkinson’s disease

, 2019; 26(20): 3702-3718.

Silvia Cerri and Fabio Blandini*


DOI: 10.2174/0929867325666180226094351



Review Article

Immune checkpoint inhibitors: Basics and challenges

, 2019; 26(17): 3009-3025.

Bin Li*, Ho Lam Chan and Pingping Chen*


DOI: 10.2174/0929867324666170804143706


Review Article

Electronic noses in medical diagnostics

, 2019; 26(1): 197-215.

Wojciech Wojnowski*, Tomasz Dymerski*, Jacek Gębicki and Jacek Namieśnik


DOI: 10.2174/0929867324666171004164636


Review Article

Applications of cellulose-based materials in sustained drug delivery systems

, 2019; 26(14): 2485-2501.

Bo Sun, Min Zhang, Jing Shen, Zhibin He, Pedram Fatehi* and Yonghao Ni


DOI: 10.2174/0929867324666170705143308


Review Article

Medical applications of collagen and collagen-based materials

, 2019; 26(3): 506-516.

Anatoly B. Shekhter, Alexey L. Fayzullin*, Marina N. Vukolova, Tatyana G. Rudenko, Varvara D. Osipycheva and Petr F. Litvitsky


DOI: 10.2174/0929867325666171205170339



Most Accessed Articles

Targeting the Nucleotide Metabolism Proteins of the NUDIX Family and SAMHD1 in Cancer

, 2021; 28(21): 4088-4116.

Prescillia Forey, Emeline Cros-Perrial, Charles Dumontet and Lars Petter Jordheim*


DOI: 10.2174/0929867328666201125120422


Drug Repurposing: Promises of Edaravone Target Drug in Traumatic Brain Injury

, 2021; 28(12): 2369-2391.

Zaynab Shakkour, Hawraa Issa, Helene Ismail, Ohanes Ashekyan, Karl John Habashy, Leila Nasrallah, Hussam Jourdi, Eva Hamade, Stefania Mondello, Mirna Sabra*, Kazem Zibara* and Firas Kobeissy*


DOI: 10.2174/0929867327666200812221022


Machine Learning-Based Scoring Functions, Development and Applications with SAnDReS

, 2021; 28(9): 1746-1756.

Gabriela Bitencourt-Ferreira, Camila Rizzotto and Walter Filgueira de Azevedo Junior*


DOI: 10.2174/0929867327666200515101820


Advances in Sickle Cell Disease Treatments

, 2021; 28(10): 2008-2032.

Aline Renata Pavan and Jean Leandro dos Santos*


DOI: 10.2174/0929867327666200610175400


New Perspectives in the Pharmacological Potential of Naringin in Medicine

, 2021; 28(10): 1987-2007.

María Angélica Rivoira, Valeria Rodriguez, Germán Talamoni and Nori Tolosa de Talamoni*


DOI: 10.2174/0929867327666200604171351


Astroglial Connexins in Neurological and Neuropsychological Disorders and Radiation Exposure

, 2021; 28(10): 1970-1986.

Yuan Duo Liu, Ge Tang, Feng Qian, Lian Liu*, Jiang Rong Huang* and Feng Ru Tang*


DOI: 10.2174/0929867327666200610175037


Convolutional Neural Network-based Virtual Screening

, 2021; 28(10): 2033-2047.

Wenying Shan, Xuanyi Li, Hequan Yao and Kejiang Lin*


DOI: 10.2174/0929867327666200526142958


The Correlation between Lipid Metabolism Disorders and Prostate Cancer

, 2021; 28(10): 2048-2061.

Justyna Dłubek, Jacek Rysz, Zbigniew Jabłonowski, Anna Gluba-Brzózka* and Beata Franczyk


DOI: 10.2174/0929867327666200806103744



A Critical Transcription Factor NF-κB as a Cancer Therapeutic Target and its Inhibitors as Cancer Treatment Options

, 2021; 28(21): 4117-4132.

Mohd Suhail*, Mohammad Tarique, Naoshad Muhammad, Huma Naz, Abdul Hafeez, Torki A. Zughaibi, Mohammad Amjad Kamal and Mohd Rehan*


DOI: 10.2174/0929867327666201111142307




Current Status of SUMOylation Inhibitors

, 2021; 28(20): 3892-3912.

Christopher M. Brackett and Brian S.J. Blagg*


DOI: 10.2174/0929867327666200810135039



Sigma-2 Receptor as a Potential Drug Target

, 2021; 28(21): 4172-4189.

Ai-Fang Chen, Wen-Hui Ma, Xiao-Yang Xie and Yun-Sheng Huang*


DOI: 10.2174/0929867327666200902172615




Editor-in-Chief

graphic
Atta-ur-Rahman, FRS
(32052 citations)
Kings College
University of Cambridge
Cambridge
(UK)
Biography
View Full Editorial Board

Nobel Laureates on Editorial Board

graphic
Prof. John Gurdon
(UK)

graphic
Prof. Jean-Marie Lehn
(France)

graphic
Prof. Ferid Murad
(USA)

COPE Compliant

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Journal History

Current Medicinal Chemistry was introduced in 1994 with the assistance of Dr. Atta-ur-Rahman, who is the current Editor-in-Chief serving since 1994.

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